What is Bumetanide and why is it prescribed?
Bumetanide is used to lower the amount of excess salt and water in your body by increasing the output of urine. It is prescribed in the treatment of edema, or fluid retention, associated with congestive heart failure and liver or kidney disease. It is also occasionally prescribed, along with other drugs, to treat high blood pressure. Bumetanide is a powerful drug. If taken in excessive amounts, it can severely decrease the levels of water and minerals, especially potassium, your body needs to function. Therefore, your doctor should monitor your dose carefully.

How should you take Bumetanide?
Follow your doctors directions for taking Bumetanide. Bumetanide can increase the frequency of urination and may cause loss of sleep if taken at night. Therefore, if you are taking a single dose of Bumetanide daily, it should be taken in the morning after breakfast. If you take more than one dose a day, take the last dose no later than 6:00 pm. If you miss a dose take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take two doses at the same time. Store Bumetanide at room temperature.

Are there any Bumetanide side effects?
Bumetanide side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. More common Bumetanide side effects may include dizziness, headache, low blood pressure, muscle cramps, and nausea. Signs of too much potassium loss are dry mouth, irregular heartbeat, muscle cramps or pains, and unusual tiredness or weakness. Less common or rare Bumetanide side effects may include abdominal pain, black stools, chest pain, dehydration, diarrhea, dry mouth, ear discomfort, fatigue, hearing loss, itching, joint pain, kidney failure, muscle and bone pain, nipple tenderness, premature ejaculation and difficulty maintaining erection, rapid breathing, skin rash or hives, sweating, upset stomach, vertigo, vomiting, and weakness.

What are the possible food and drug interactions when taking Bumetanide?
If Bumetanide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Be sure to inform your doctor of all the prescription and over the counter medications you are taking. It is especially important to check with your doctor before combining Bumetanide with Blood pressure medications (such as Vasotec and Tenormin), Indomethacin (Indocin) and other nonsteroidal anti-inflammatory drugs, and Probenecid (Benemid). The combination of Bumetanide and certain antibiotics or cisplatin (Platinol) may increase the risk of hearing loss. Because Bumetanide can lower potassium levels, the combination of Bumetanide and digitalis or digoxin (Lanoxin) may increase the risk of changes in heartbeat. The combination of Bumetanide and lithium (Lithonate) may increase the levels of lithium in the body, causing it to become poisonous.

Are there any special warnings about Bumetanide?
If you are allergic to sulfur-containing drugs such as sulfonamides, check with your doctor before taking Bumetanide. Bumetanide can decrease the number of platelets in your blood. Your doctor should monitor your blood status regularly. Bumetanide can cause a loss of potassium from the body. Your doctor may recommend foods or fluids high in potassium or may want you to take a potassium supplement to help prevent this. Follow your doctor's recommendation carefully. While taking this medication you may feel dizzy or light-headed or actually faint when getting up from a lying or sitting position. If getting up slowly does not help or if this problem continues, notify your doctor.

Information on this website is provided for educational purposes and should not replace discussions with your doctor.


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