|
|
|
Entacapone |
|
|
What is Entacapone and why is it prescribed? Entacapone is used for Parkinson's disease. It is prescribed when doses of the combination drug levodopa/carbidopa (Sinemet) begin to wear off too soon. By extending the effect of each dose of Sinemet, it frees the patient from the stiffness and tremors of Parkinson's for a longer period of time. Entacapone works by inhibiting the effect of an enzyme that breaks down the levodopa in Sinemet. Entacapone has no effect on Parkinson's disease when used by itself. Entacapone's value lies in its ability to extend Sinemet's effectiveness when it begins to decline. Entacapone is helpful only when taken with the other drug, and has no benefit when used alone. How should you take Entacapone? Follow your doctors directions for taking Entacapone. Entacapone should be taken with each dose of Sinemet. It can be taken up to 8 times per day, with or without food. If you miss a dose take it along with a dose of Sinemet as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take two doses at the same time. Store Entacapone at room temperature. Are there any Entacapone side effects? Entacapone side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. More common Entacapone side effects may include abdominal pain, back pain, constipation, diarrhea, discoloration of urine, dizziness, nausea, onset of new movement disorders, tired feeling, and vomiting. Less common Entacapone side effects may include agitation, anxiety, bruises, difficulty breathing, dry mouth, gas, increased sweating, indigestion, infection, sleepiness, stomach distress, taste changes, weakness, and worsening of Parkinson's disease. What are the possible food and drug interactions when taking Entacapone? If Entacapone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Be sure to inform your doctor of all the prescription and over the counter medications you are taking. It is especially important to check with your doctor before combining Entacapone with Antidepressant drugs classified as MAO inhibitors (including Nardil and Parnate, Comtan can be used with a special type of MAO inhibitor called selegiline, which is used for treating Parkinson's disease), Bitolterol (Tornalate), Certain antibiotics (including ampicillin and erythromycin), Cholestyramine (Questran), Methyldopa (Aldomet), Isoproterenol (Isuprel), or Probenecid (Benemid). Are there any special warnings about Entacapone? Use of Entacapone can cause low blood pressure, with symptoms such as dizziness, nausea, fainting, and sweating. Be careful when standing up after you have been sitting or lying down. See how Entacapone affects you before you drive a car or operate machinery. Nausea and diarrhea are especially common side effects of Entacapone, developing in more than 10 percent of those taking it. In rare cases, the problem is severe. Entacapone may also cause hallucinations, and occasionally triggers new movement disorders. In about 10 percent of those taking it, it has the harmless side effect of turning the urine a brownish-orange color. An abrupt discontinuation of Entacapone can cause a reappearance of Parkinson's symptoms. If a decision is made to discontinue the drug, it should be withdrawn slowly, under a doctor's supervision. Entacapone is not intended for use in children. |
|
|
Information on this website is provided for educational purposes and should not replace discussions with your doctor. |
|
|
Copyright 2008 MyMedications.net. All rights reserved. |
|
