What is Prevpac and why is it prescribed?
Prevpac is a prepackaged combination of drugs designed to cure duodenal ulcers caused by H. pylori bacteria, the most common source of ulcers. With two antibiotics and an acid-blocking agent, Prevpac will eradicate the H. pylori infection and improve your odds of remaining ulcer-free. This type of therapy is usually reserved for people with an active ulcer and those who've had one for at least a year. Prevpac will work only if you take all the medications as prescribed and finish your entire course of therapy. If you stop too soon, the ulcer may not heal completely and your symptoms may return.

How should you take Prevpac?
Follow your doctors directions for taking Prevpac. Each pack contains a full day's supply of medication, consisting of two 30-milligram capsules of lansoprazole (Prevacid), four 500-milligram capsules of amoxicillin, and two 500-milligram tablets of clarithromycin (Biaxin). Take half the supply before breakfast and the remainder before dinner. Swallow each pill whole; do not crush or chew. If you miss a dose take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at the same time. Store Prevpac at room temperature, away from light and moisture.

Are there any Prevpac side effects?
Prevpac side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. More common Prevpac side effects may include diarrhea, headache, and taste disturbances. Less common and rare Prevpac side effects may include abdominal pain, confusion, dark stools, dizziness, dry mouth, mouth infection, mouth sores, muscle aches, rectal itching, nausea, respiratory problems, skin reactions, thirst, tongue swelling or discoloration, vaginal infections, vaginal inflammation, and vomiting.

What are the possible food and drug interactions when taking Prevpac?
If Prevpac is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Be sure to inform your doctor of all the prescription and over the counter medications you are taking. It is especially important to check with your doctor before combining Prevpac with Ampicillin, Astemizole (Hismanal), Blood-thinning pills (such as Warfarin/Coumadin), Bromocriptine (Parlodel), Carbamazepine (Tegretol), Cisapride (Propulsid), Cyclosporine (Neoral, Sandimmune), Digoxin (Lanoxin), Disopyramide (Norpace), Ergotamine-based drugs for migraine (such as Cafergot, D.H.E. 45 Injection, Ergostat, and Migranal Nasal Spray), Ketoconazole (Nizoral), Iron supplements, Lovastatin (Mevacor), Phenytoin (Dilantin), Pimozide (Orap), Sucralfate (Carafate), Tacrolimus (Prograf), Terfenadine (Seldane), Theophylline (Theo-Dur, Theolair), or Triazolam (Halcion).

Are there any special warnings about Prevpac?
If you develop severe diarrhea after taking Prevpac, call your doctor. Prevpac therapy is not recommended if you have severe kidney disease. Use Prevpac with caution if you are over 65 years old.

Information on this website is provided for educational purposes and should not replace discussions with your doctor.


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