Salsalate

 
What is Salsalate and why is it prescribed?
Salsalate, a nonsteroidal anti-inflammatory drug, is used to relieve the symptoms of rheumatoid arthritis, osteoarthritis, and other rheumatic disorders. Salsalate contains salicylate, an ingredient that may be associated with the development of Reye's syndrome. It occurs mostly in children who have taken aspirin or other medications containing salicylate to relieve symptoms of the flu or chickenpox. Do not take Salsalate if you have flu symptoms or chickenpox.

How should you take Salsalate?
Follow your doctors directions for taking Salsalate. Food may slow its absorption. However, your doctor may ask you to take Salsalate with food in order to avoid upset stomach. If you miss a dose take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take two doses at once. Store Salsalate at room temperature.

Are there any Salsalate side effects?
Salsalate side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Salsalate side effects may include hearing impairment, nausea, rash, ringing in the ears, and vertigo.

What are the possible food and drug interactions when taking Salsalate?
If Salsalate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Be sure to inform your doctor of all the prescription and over the counter medications you are taking. It is especially important to check with your doctor before combining Salsalate with ACE inhibitor-type blood pressure drugs (such as Capoten and Vasotec), Acetazolamide (Diamox), Aspirin and other drugs containing salicylates (such as Bufferin and Empirin), Blood-thinning medications (such as Coumadin), Medications for gout (such as Zyloprim and Benemid), Methotrexate (Rheumatrex), Naproxen (Anaprox, Naprosyn), Oral diabetes drugs (such as Glucotrol and Tolinase), Penicillin (Pen-Vee K), Phenytoin (Dilantin), Steroids (such as Deltasone and Decadron), Sulfinpyrazone (Anturane), or Thyroid medications (such as Synthroid).

Are there any special warnings about Salsalate?
Use Salsalate with extreme caution if you have chronic kidney disease or a peptic ulcer. Salicylates occasionally cause asthma in people who are sensitive to aspirin. Although Salsalate contains a salicylate, it is less likely than aspirin to cause this reaction.
 

Information on this website is provided for educational purposes and should not replace discussions with your doctor.

 

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