Serophene |
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What is Serophene and why is it prescribed? Serophene is prescribed for the treatment of ovulatory failure in women who wish to become pregnant and whose husbands are fertile and potent. Properly timed sexual intercourse is very important to increase the chances of conception. The likelihood of conception diminishes with each succeeding course of treatment. Your doctor will determine the need for continuing therapy after the first course. If you do not ovulate after 3 courses or do not become pregnant after 3 ovulations, your doctor will stop the therapy. How should you take Serophene? Follow your doctors directions for taking Serophene. If you miss a dose take it as soon as you remember. If it is time for your next dose, take the 2 doses together and go back to your regular schedule. If you miss more than 1 dose, contact your doctor. Store Serophene at room temperature in a tightly closed container, away from light, moisture, and excessive heat. Are there any Serophene side effects? Serophene side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. More common Serophene side effects include abdominal discomfort, enlargement of the ovaries, and hot flushes. Less common Serophene side effects include abnormal uterine bleeding, breast tenderness, depression, dizziness, fatigue, hair loss, headache, hives, inability to fall or stay asleep, increased urination, inflammation of the skin, light-headedness, nausea, nervousness, ovarian cysts, visual disturbances, vomiting, and weight gain. What are the possible food and drug interactions when taking Serophene? If Serophene is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Be sure to inform your doctor of all the prescription and over the counter medications you are taking. No food or drug interactions have been reported. Are there any special warnings about Serophene? Your doctor will evaluate you for normal liver function and normal estrogen levels before considering you for treatment with Serophene. Your doctor will also examine you for pregnancy, ovarian enlargement, or cyst formation prior to treatment with this drug and between each treatment cycle. He or she will do a complete pelvic examination before each course of Serophene. Serophene treatment increases the possibility of multiple births; also, birth defects have been reported following treatment to induce ovulation with Serophene, although no direct effects of the drug on the unborn child have been established. Because blurring and other visual symptoms may occur occasionally with Serophene treatment, you should be cautious about driving a car or operating dangerous machinery, especially under conditions of variable lighting. If you experience visual disturbances, notify your doctor immediately. Symptoms of visual disturbance may include blurring, spots or flashes, double vision, intolerance to light, decreased visual sharpness, loss of peripheral vision, and distortion of space. Your doctor may recommend a complete evaluation by an eye specialist. Ovarian hyperstimulation syndrome (or OHSS, enlargement of the ovary) has occurred in women receiving treatment with Serophene. OHSS may progress rapidly and become serious. The early warning signs are severe pelvic pain, nausea, vomiting, and weight gain. Symptoms include abdominal pain, abdominal enlargement, nausea, vomiting, diarrhea, weight gain, difficult or labored breathing, and less urine production. If you experience any of these warning signs or symptoms, notify your doctor immediately. To lessen the risks associated with abnormal ovarian enlargement during treatment with Serophene, the lowest effective dose should be prescribed. Women with the hormonal disorder, polycystic ovarian syndrome, may be unusually sensitive to certain hormones and may respond abnormally to usual doses of this drug. If you experience pelvic pain, notify your doctor. He may discontinue your use of Serophene until the ovaries return to pretreatment size. Because the safety of long-term treatment with Serophene has not been established, your doctor will not prescribe more than about 6 courses of therapy. Prolonged use may increase the risk of a tumor in the ovaries. |
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