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Topiramate |
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What is Topiramate and why is it prescribed? Topiramate is an antiepileptic drug, prescribed to control both the mild attacks known as partial seizures and the severe tonic-clonic convulsions known as grand mal seizures. Topiramate is typically added to the treatment regimen when other drugs fail to fully control a patient's attacks. Do not abruptly stop taking Topiramate. If the drug isn't withdrawn gradually, the frequency of your seizures could increase. How should you take Topiramate? Follow your doctors directions for taking Topiramate. It is important to take Topiramate exactly as prescribed. It can be taken with or without food. Avoid breaking the tablets; the medication has a bitter taste. Topiramate capsules may be swallowed whole, or the capsule may be opened and its contents sprinkled on a teaspoonful of soft food. To open the capsule, hold it so you can read the word "top" and carefully twist off the clear portion of the capsule. The drug and food mixture should be swallowed whole and not chewed. Do not store the mixture for future use. Topiramate increases your risk of developing kidney stones. To prevent this problem, be sure to take this medication with plenty of fluids. If you miss a dose take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take two doses at once. Store Topiramate at room temperature in a tightly closed container. Protect the tablets from moisture. Are there any Topiramate side effects? Topiramate side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Some side effects, such as fatigue, are more likely to surface with high doses of Topiramate. Others occur regardless of dosage. While many tend to disappear after the first 8 weeks of therapy, it's still important to report them to your doctor. More common Topiramate side effects may include abdominal pain, abnormal coordination, abnormal vision, agitation, anxiety, appetite loss, back pain, breast pain, chest pain, confusion, constipation, depression, difficulty with concentration, difficulty with memory, dizziness, double vision, drowsiness, fatigue, flu-like symptoms, indigestion, language problems, leg pain, loss of coordination, menstrual problems, mood problems, nausea, nervousness, nose inflammation, rash, sinusitis, slowing of movements, sore throat, speech problems, tingling or burning sensations, tremors, weakness, and weight loss. Less common Topiramate side effects may include abnormal gait, abnormal menstrual bleeding, acne, aggressiveness, allergy, apathy, bladder infection, changes in taste, bloody urine, body odor, decreased awareness, decreased mobility, decreased sensitivity, diarrhea, digestive inflammation, dry mouth, exaggerated sense of well being, eye pain, feelings of illness, feelings of unreality, fever, fluid retention, frequent urination, gas, gum inflammation, hair loss, hallucinations, headache, hearing difficulties, hot flushes, hyperactivity, impotence, increased sweating, involuntary muscle movement, irritable bladder, joint pain, kidney stones, loss of balance, loss of consciousness, low sex drive, mood swings, muscle ache, muscle tension, muscle weakness, nosebleeds, painful or difficult urination, personality problems, pinkeye, ringing in the ears, sensitivity to touch, severe itching, shivers, shortness of breath, sleeplessness, suicidal tendencies, swelling, upper respiratory infection, urinary infection, urinary incontinence, vaginal infection, vomiting, and weight gain. In children, the more common Topiramate side effects are abnormal gait, aggressiveness, behavior problems, confusion, constipation, difficulty concentrating, difficulty with memory, difficulty sleeping, dizziness, drowsiness, fatigue, increased muscle movement, increased saliva, injury, loss of appetite, loss of coordination, nausea, nervousness, nosebleed, pneumonia, rash, speech problems, urinary incontinence, viral infection, and weight loss. Other, less common Topiramate side effects in children include allergic reaction, digestive inflammation, increased thirst, skin disorders, slowing of movement, vaginal discharge, vision disorders, and weakened reflexes. Topiramate has also been known to cause a number of very rare side effects in adults and children. If you develop any unfamiliar problems while taking Topiramate, report them to your doctor. What are the possible food and drug interactions when taking Topiramate? If Topiramate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Be sure to inform your doctor of all the prescription and over the counter medications you are taking. It is especially important to check with your doctor before combining Topiramate with Acetazolamide (Diamox), Carbamazepine (Tegretol), Dichlorphenamide (Daranide), Digoxin (Lanoxin), Metformin (Glucophage), Phenytoin (Dilantin), Oral contraceptives, or Valproic acid (Depakene). Topiramate can depress the central nervous system. Be extremely cautious about combining Topiramate with alcohol, sedatives, tranquilizers, and other central nervous system depressants. Are there any special warnings about Topiramate? Because Topiramate sometimes causes confusion, dizziness, fatigue, and problems with coordination and concentration, you should not drive, operate machinery, or participate in any hazardous activity that requires full mental alertness until you are certain how the drug affects you. Topiramate has been known to trigger severe nearsightedness along with increased pressure inside the eye. The problem usually occurs within 1 month of starting treatment. If you develop blurred vision or eye pain, call your doctor immediately. Discontinuation of the drug may be necessary to prevent permanent vision loss. Tell your doctor if you have kidney problems or if you are on hemodialysis. Your dosage of Topiramate may need adjustment. Also make sure the doctor is aware of any liver disorder you may have. Topiramate must be used cautiously by individuals with impaired liver function. |
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Information on this website is provided for educational purposes and should not replace discussions with your doctor. |
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