Uniretic

 
What is Uniretic and why is it prescribed?
Uniretic combines two types of blood pressure medication. The first, moexipril hydrochloride, is an ACE inhibitor. It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form (angiotensin II) that increases salt and water retention in the body and causes the blood vessels to constrict. To aid in clearing excess water from the body, Uniretic also contains hydrochlorothiazide, a diuretic that promotes production of urine. Diuretics often wash too much potassium out of the body along with the water. However, the ACE inhibitor part of Uniretic tends to keep potassium in the body, thereby canceling this unwanted effect. Uniretic is not used for the initial treatment of high blood pressure. It is saved for later use, when a single blood pressure medication is not sufficient for the job. You must take Uniretic regularly for it to be effective. Uniretic does not cure high blood pressure but it keeps it under control.

How should you take Uniretic?
Follow your doctors directions for taking Uniretic. Take Uniretic once a day, 1 hour before a meal. Try not to miss any doses. Stopping Uniretic suddenly could cause a rise in blood pressure. If you miss a dose take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take two doses at the same time. Store Uniretic at room temperature, away from moisture, in a tightly closed container.

Are there any Uniretic side effects?
Uniretic side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Common Uniretic side effects may include abdominal pain, back pain, bronchitis, chest pain, cough, diarrhea, dizziness, fatigue, fever, flu symptoms, headache, impotence, increased blood sugar, indigestion, infection, inflammation of the nasal passages, pain, rash, sinus inflammation, sore throat, swelling, tension, upper respiratory tract infection, urinary tract infection, and vertigo. Rare Uniretic side effects may include constipation, difficulty breathing, dizziness upon standing, drowsiness, eczema, fainting, flushing, gynecological problems, inflammation of the digestive tract, insomnia, itching, loss of strength, low blood counts, muscle aches, nosebleed, pinkeye, pneumonia, rapid heartbeat, sweating, and urinary problems.

What are the possible food and drug interactions when taking Uniretic?
If Uniretic is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Be sure to inform your doctor of all the prescription and over the counter medications you are taking. It is especially important to check with your doctor before combining Uniretic with ACTH, Alcohol, Barbiturates (such as phenobarbital or Seconal), Cholestyramine (Questran), Colestipol (Colestid), Diabetes medications (such as glyburide and insulin), Guanabenz (Wytensin), Lithium (Lithobid, Lithonate), Narcotics (such as Percocet), Nonsteroidal anti-inflammatory painkillers (such as Motrin and Naprosyn), Potassium-sparing diuretics (such as Dyrenium or Moduretic), Potassium supplements (such as Slow K), Propantheline (Pro-Banthine), Salt substitutes containing potassium, or Steroid medications such as prednisone (Deltasone).

Are there any special warnings about Uniretic?
Contact your doctor immediately if you develop swelling around your lips, tongue, or throat, or in your arms and legs, or if you begin to have difficulty breathing or swallowing. You may need emergency room treatment. If you have poor kidneys, use Uniretic with caution. For people with severe kidney disease, Uniretic is not recommended at all. Your doctor should test your kidney function at the start of treatment, and continue to monitor it as long as you take the drug. Uniretic can cause light-headedness, especially during the first few days of treatment. If you faint, stop taking the medication and call your doctor immediately. Uniretic can cause a severe drop in blood pressure if you lose too much liquid through excessive sweating, severe diarrhea, or vomiting. Contact your doctor immediately if you develop one of these problems. Low blood pressure is especially dangerous if you have congestive heart failure or other heart conditions. Your doctor should monitor your pressure with extra care if that's the case. Uniretic should be used with caution if you are on dialysis. There have been reports of extreme allergic reactions during dialysis in people taking ACE inhibitors such as the one in Uniretic. A severe reaction is also more likely if you have ever had desensitization treatments with bee or wasp venom. If you have liver disease or a disease of connective tissue called lupus erythematosus, Uniretic should be used with caution. Tell your doctor immediately if you notice a yellowish color to your skin or the whites of your eyes. While taking Uniretic, do not use potassium supplements, salt substitutes that contain potassium, or diuretics that leave potassium levels high unless your doctor recommends it. Diuretics such as the one in Uniretic sometimes leave the body with too little sodium, chloride, or potassium, leading to symptoms such as dry mouth, thirst, weakness, sluggishness, drowsiness, restlessness, muscle pain or cramps, muscular fatigue, low urine output, rapid heartbeat, nausea, and vomiting. If you develop any of these symptoms, alert your doctor. Uniretic can aggravate diabetes or high cholesterol. If you have one of these conditions, your doctor should closely monitor your blood sugar or cholesterol levels. If you develop unusual or increased coughing, tell your doctor. Contact your doctor immediately if you develop a sore throat or fever; they could be signs of a more serious illness. If you are having a surgical procedure that requires anesthesia, make sure the doctor knows that you are taking Uniretic.
 

Information on this website is provided for educational purposes and should not replace discussions with your doctor.

 

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