Zocor |
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What is Zocor and why is it prescribed? Zocor is a cholesterol-lowering drug. Your doctor may prescribe Zocor in addition to a cholesterol-lowering diet if your blood cholesterol level is too high, and if you have been unable to lower it by diet alone. In people with high cholesterol and heart disease, Zocor reduces the risk of heart attack, stroke and "mini-stroke" and can stave off the need for bypass surgery or angioplasty to clear clogged arteries. Zocor is usually prescribed only if diet, exercise, and weight-loss fail to bring your cholesterol level under control. To get the full benefit of Zocor, you need to stick to the diet and exercise program prescribed by your doctor. How should you take Zocor? Follow your doctors directions for taking Zocor. If you miss a dose take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once. Store Zocor at room temperature. Are there any Zocor side effects? Zocor side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. More common Zocor side effects may include abdominal pain and headache. Less common Zocor side effects may include constipation, diarrhea, gas, muscle weakness with rash, nausea, upper respiratory infection, upset stomach, and weakness. What are the possible food and drug interactions when taking Zocor? If Zocor is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Be sure to inform your doctor of all the prescription and over the counter medications you are taking. Zocor tends to enhance the effects of the blood-thinning drug Coumadin and the heart medication Lanoxin. Combining it with the following drugs increases the chance of muscle damage: Amiodarone (Cordarone), Clarithromycin (Biaxin), Clofibrate (Atromid-S), Cyclosporine (Sandimmune, Neoral), Erythromycin (PCE and others), Fenofibrate (Tricor), Gemfibrozil (Lopid), Itraconazole (Sporanox), Ketoconazole (Nizoral), Nefazodone (Serzone), Nicotinic acid or niacin (Niaspan), Protease inhibitors (including Agenerase, Crixivan, Fortovase, Invirase, Norvir, and Viracept), or Verapamil (Calan). If you are taking Zocor with any of these drugs (or with large quantities of grapefruit juice) alert your doctor immediately at the first sign of muscle pain or weakness. If you need to take erythromycin, Biaxin, Nizoral, or Sporanox, the doctor may temporarily take you off Zocor. Are there any special warnings about Zocor? Because Zocor may damage the liver, your doctor may order a blood test to check your liver enzyme levels before you start taking the drug. Blood tests will probably be done before your treatment is started and at periodic intervals for a year after your final dosage increase. If your liver enzyme levels rise too high, your doctor may tell you to stop taking Zocor. Since Zocor may cause damage to muscle tissue, be sure to tell your doctor of any unexplained muscle tenderness, weakness, or pain right away, especially if you also have a fever or feel sick. Your doctor may want to do a blood test to check for signs of muscle damage. If you are scheduled for major surgery, your doctor will have you stop taking Zocor a few days before the operation. |
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